Article Date: 01 Feb 2013 - 2:00 PST Current ratings for:
Toward A Better Cyanide Antidote For Terrorist Attacks And Other Mass Casualty Events
In an advance toward closing a major gap in defenses against terrorist attacks and other mass casualty events, scientists are reporting discovery of a promising substance that could be the basis for development of a better antidote for cyanide poisoning. Their report, which describes a potential antidote that could be self-administered, much like the medication delivered by allergy injection pens, appears in ACS' Journal of Medicinal Chemistry.
Steven E. Patterson, Ph.D., and colleagues at the University of Minnesota Center for Drug Design explain that the only existing antidotes for cyanide - recognized as a high-risk substance for potential use by terrorists - must be administered by intravenous infusion. That procedure requires highly trained paramedical personnel and takes time. Cyanide, however, is a fast-acting poison. In a situation involving mass casualties, only a limited number of victims could be saved. Patterson's team thus sought an antidote that could be administered by intra-muscular (IM) injection, a simpler procedure that could be administered rapidly to a large number of victims or even be self-administered.
Their report describes discovery of a substance, sulfanegen TEA, "which should be amenable for development as an IM injectable antidote suitable for treatment of cyanide victims in a mass casualty setting. Further development, including efficacy in lethal cyanide animal models, will be reported at a later date."
The authors acknowledge financial support from the National Institutes of Health through the National Institute of Neurological Disorders and Stroke (award #UO1NS058087-05).
Article adapted by Medical News Today from original press release. Click 'references' tab above for source.Visit our bio-terrorism / terrorism section for the latest news on this subject. “Cyanide Antidotes for Mass Casualties: Water-Soluble Salts of the Dithiane (Sulfanegen) from 3- Mercaptopyruvate for Intramuscular Administration”,
Steven E. Patterson et al.
Journal of Medicinal Chemistry. DOI: 10.1021/jm301633x Publication Date (Web): January 9, 2013 Please use one of the following formats to cite this article in your essay, paper or report:
MLA
5 Jul. 2013.
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posted by Susan King on 12 Feb 2013 at 10:53 am
If we eat apricot kernals, we up our resistance to cyanide. I eat apricot kernals. The cult told me that they had put cyanide into my chocolate soymilk, but that it didn't do anything to me at all.
Start by eating only 1 or 2 at a time, per day. Then after a week, eat 3 within 25 minutes. Then after 2 weeks of this eat 4 within 35 minutes, etc. GO SLOWLY ! ! DON'T PUSH IT ! I take absolutely no responsibility for you if you eat way too much and kill yourself..... I can eat a lot of it...don't bet that your tolerance will be identical to mine..This information is for your reference only, and is not to be used if you have no common sense, and cannot build up your immunity slowly on your on !
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